OBIO® Drives AI Innovation in Critical Care with The Ottawa Hospital’s Use of the Extubation Advisor

OBIO® Drives AI Innovation in Critical Care with The Ottawa Hospital’s Use of the Extubation Advisor
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TORONTO – OBIO®, through the Biotechnology and Life Sciences Commercialization Center of Excellence (LSCTC), supports the Extubation Consultant (EA) accreditation at The Ottawa Hospital (TOH). The AI-powered clinical support tool was developed by Canadian company Therapeutic Monitoring Systems Inc. (TMS), to assist physicians in making extubation decisions in intensive care units.

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EA is certified after completing successful evaluations at TOH and Unity Health through OBIO’s Early Adopter Health Network™ (EAHN™) program. EAHN™ is supported by the Canadian Government through Federal Economic Development Agency for Southern Ontario (FedDev Ontario), and LSCTC is supported by the Government of Ontario.

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Removing a patient from mechanical ventilation, known as extubation, is a complex process in critical care. The EA, based on research by Dr. Andrew J. E. Seely, a thoracic surgeon and intensive care unit (ICU) physician at TOH and CEO of TMS, uses artificial intelligence to analyze a patient’s respiratory data and help doctors make extubation decisions. This reduces uncertainty by identifying patients at higher or lower risk for extubation failure, leading to better patient outcomes and more efficient use of ICU resources.

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“This tool represents more than a decade of research on how to direct patient data to better care.”

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said Dr. Seely, CEO of Therapeutic Monitoring Systems (TMS) and Chief of Thoracic Surgery at TOH.

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“Extubation decisions are some of the most difficult decisions we make in the ICU, and the Extubation Advisor gives clinicians access to real-time evidence-based predictions to help guide those moments. We are grateful to OBIO® for helping to translate research into practice in a way that can benefit patients across Canada and internationally.”

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TOH is one of the first hospitals to implement EA as part of a real-world evaluation. This technology complements existing clinical judgment by providing personalized, data-driven insights that may help reduce ICU lengths of stay and reduce ventilation-related complications.

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“The Ottawa Hospital continues to be a leader in medical innovation, and the Extubation Advisor is a powerful example of how we can use technology to enhance care in the ICU.”

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said Dr. Kwadwo Kyeremanteng, chief of critical care at The Ottawa Hospital.

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“By supporting more informed, individualized decisions, this tool has the potential to improve patient outcomes and make our system more efficient.”

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EA has received regulatory clearance from both Health Canada and the European Union. TMS is now working with additional healthcare partners in Canada and internationally to expand its use and widespread adoption.

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“This partnership with The Ottawa Hospital and Therapeutic Monitoring Systems is a powerful demonstration of how AI-powered tools in Ontario can be successfully integrated into critical care to improve patient outcomes.”

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said Dr. Maura Campbell, President and CEO of OBIO®.

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“Through our EAHN™ and LSCTC programs, we are proud to support the Extubation Consultant assessment and certification, demonstrating our commitment to translating cutting-edge research into real-world healthcare solutions that enhance clinical decision-making and make our hospital systems more efficient.”

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“Congratulations to OBIO®, The Ottawa Hospital, and Therapeutic Monitoring Systems on this important achievement,”

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said the Honorable Ivan Solomon, Minister of Artificial Intelligence and Digital Innovation and Minister Responsible for the Federal Economic Development Agency for Southern Ontario.

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“The Extubation Advisor is a Canadian-made, AI-powered technology that improves patient care. Our government will continue to support partnerships that translate research into real-world solutions, ensuring Canada remains a leader in health innovation.”

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About Therapeutic Monitoring Systems Company

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Therapeutic Monitoring Systems (TMS), a Canadian company based in Ottawa, Ontario, Canada, develops regulatory-approved predictive clinical decision support software (CDSS) tools.

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TMS is transforming the way patient monitoring data is used to significantly improve patient care, by converting contrast waveforms (such as EKG) (using variance analysis) into predictive CDSSs (using AI machine learning), which are then implemented at the bedside of acutely ill patients in the intensive care unit (ICU) and emergency department (ED).

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TMS’s patented software technology combines waveform processing, variance analysis, and predictive modeling to convert routinely collected (and routinely discarded) waveforms into a measure of the risk of subsequent deterioration for an individual patient. TMS provides predictive support for bedside clinical decisions in a targeted manner to address unresolved issues, with low variability providing a sensitive measure of the severity of a patient’s illness and/or frailty. TMS CDSS tools are integrated with existing care delivery processes, thus providing clinical decision support at the time clinicians make the decision. TMS CDSS tools are designed to enhance the effectiveness of treatment plans and reduce harmful and costly adverse events.

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TMS is collaborating with OBS Medical, the Ottawa Hospital Research Institute (OHRI) and clinicians and scientists globally to research, develop and commercialize this new technology, to help transform monitoring and improve care.

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To learn more, visit: therapeutic monitoring.com.

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About The Ottawa Hospital

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The Ottawa Hospital (TOH) is one of Canada’s premier teaching and research hospitals where we are guided by our vision to provide our loved ones with the world-class, compassionate care we all desire. Our multi-campus hospital, affiliated with the University of Ottawa, is home to an internationally accredited Regional Trauma Centre, Cancer Centre, and Discovery Center.

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