Inside the Mind of Dr. Phyllis Pobee: The Science Behind GeneLean360°

Dr. Phyllis Poppy, MD, is a triple-board-certified physician and founder and CEO of GeneLean360°, a science-based weight loss company that helps women transform their health through genetics and cellular insight.

She resides in Toronto, Canada, is certified in Family Medicine, Aesthetic Medicine, and Obesity Medicine, and is the author of Lean Genes.

Her journey did not begin in the laboratory, but in her private life. After years of doing “everything right” and still struggling with her weight, Dr. Poppy turned to genetic testing to uncover the truth behind her body’s resistance. What she discovered changed everything: her unique biology held the key. By learning how her genes affected her metabolism, she lost 100 pounds and kept the weight off.

This discovery became the basis of GeneLean360°, a comprehensive 4-month weight loss program designed for women over 30 years of age. It blends genetics, mindset and lifestyle to achieve lasting results without extreme dieting or deprivation.

Dr. Bobbie leads her company with a mission to help women stop fighting their biology and start working with it. She believes in “science with soul” – combining data-driven rigor with empathy and education. With GeneLean360°, she redefines how women view weight loss: not as a punishment, but as a path to understanding their bodies.

Her vision is simple yet profound – a world where women live in harmony with their genes, guided by knowledge, compassion and self-confidence.

Q&A with GeneLean360° founder and physician leader

How did your journey with medicine and genetics begin?

I have always loved science and understanding how the body works. But the real turning point for me came when I was struggling with my weight. I was a practicing physician, doing everything “right” – eating well, exercising – but nothing changed. He was humble. Eventually, I discovered that my genes were affecting how my body responded to food and exercise. Once I understood that, everything clicked.

What inspired you to start GeneLean360°?

After losing 100 pounds by applying genetic insights to my life, I realized that other women needed the same understanding. I have established Jane Lin 360° To help women stop guessing and start using science to make real progress. Many of my clients are women over the age of 30 who have tried every diet imaginable. They are not lazy or unmotivated, they are simply fighting against their own biology.

Can you explain how the GeneLean360° approach works?

It starts with cellular health. We start with a simple at-home urine test to measure inflammation and oxidative stress, two key indicators of how well the body is functioning. We then meet face-to-face to interpret the results and determine what is hindering fat loss. If appropriate, we recommend genetic testing to determine how your DNA affects metabolism, appetite and hormones. From there, we design a precise plan tailored to your body.

You often say “knowledge is by the soul.” What does that mean?

For me, it’s about balance. Science gives us the data – the what and why – but the spirit gives us empathy. My work is rooted in empathy because transformation is personal. We’re not just changing the numbers on a massive scale; We help women rebuild their relationship with themselves.

How do you see the weight loss industry changing?

The industry is shifting from one-size-fits-all diets to personalized wellness. People are tired of extremism. They want solutions that fit their biology and lifestyle. Genetics is the future because it explains why two people can do the same thing and get completely different results.

What challenges did you face in building a science-based health project?

Educating people was the biggest obstacle. We’ve been conditioned to believe that losing weight is about willpower. it’s not. It’s about biology. Helping women ditch outdated diet myths and embrace a more informed, compassionate approach takes time—but it’s worth it.

What makes GeneLean360° special in your opinion?

We combine advanced diagnostics with emotional awareness. Most programs focus only on food or exercise. We go deeper, looking at cellular health, hormones, stress, and even mental health. I often tell clients, “If your cells are inflamed, you won’t be able to burn fat efficiently.” This is the level of precision we work with.

What kind of results do your clients experience?

They don’t just lose weight, they gain clarity. Many say that this is the first time they really understand their bodies. They stop feeling guilty for what is not their fault. When you see that shift – from frustration to empowerment – that is success.

What is your advice to women starting their health journey?

Start by listening to your body. Pay attention to how different foods, stress and sleep affect you. Don’t strive for perfection; Chasing understanding. The more you learn about your biology, the more sustainable your choices will become.

Where do you see GeneLean360° headed in the next few years?

I want to see gene-based wellness become mainstream. Imagine a world where your doctor not only asks what you eat, but also asks you how your DNA processes what you eat. This is the future – health guided by genetic truth and personalized care.